The owners announced plans for the hotel's demolition on August 21, 1964, leading to a significant public outcry and protests. On December 16, 1964, the owners announced that the hotel would be replaced by a 48-story office tower, designed by Edward Durell Stone to house the Eastern headquarters of General Motors.
The hotel remained open through the 1964 New York World's Fair, finally closing in October 1965. It was demolished in late 1965 and early 1966 and replaced with the General Motors Building, completed in 1968.