Quakers, despite their small numbers, have wielded considerable influence in history, particularly in reform movements. Founded by William Penn in 1682, Pennsylvania provided a sanctuary for Quakers to freely practice their faith. Quakers have been pivotal in advocating for abolitionism, women's rights, and peace. They've also championed education, prison reform, and humane treatment of the mentally ill, often establishing or reforming institutions to advance these causes. Additionally, Quaker entrepreneurs played a significant role in propelling the Industrial Revolution, particularly in England and Pennsylvania.